Research Article

Analysis of Immune Gene Expression Subtypes Reveals Osteosarcoma Immune Heterogeneity

Figure 1

The immune subtypes and gene modules in OS. (a) The cumulative distribution function (CDF) curve of training sample; (b) CDF delta area curve of training sample. Delta area curve of consensus clustering indicates the relative change in area under the CDF curve for each category number k compared with k − 1. The horizontal axis represents the category number k, and the vertical axis represents the relative change in area under the CDF curve; (c) Sample clustering heat map when consensus k = 5; (d) Kaplan–Meier curves for five immune subtypes prognosis. (e). CDF curve of immune gene; (f) CDF delta area curve of immune gene; (g) Univariate Cox analysis results of gene modules.