Analysis of Immune Gene Expression Subtypes Reveals Osteosarcoma Immune Heterogeneity

Figure 4

The immune landscape of OS and the intracluster heterogeneity within immune subtype 2. (a) The immune landscape of OS: each point represents a patient with colors corresponding to the immune subtype defined previously. (b) Patients of immune subtype 2 could be further stratified into 2 subgroups based on their location in the immune landscape. (c) Gene module expression patterns were shown to illustrate the intracluster heterogeneity of immune subtype 2. (d) The two subgroups of patients in immune subtype 2 as stratified by the immune landscape were associated with distinct prognoses. Log-rank value was calculated among subgroup stratification.

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