Research Article

Prognostic Implications of ALDH1 and Notch1 in Different Subtypes of Oral Cancer

Table 1

Distribution of the frequency of ALDH1 and Notch1 immunoexpression in the 63 patients with subtypes of oral cancer.

Antibodies and immunoexpressionSubtypes of oral cancerp
WDOSCC
N (%)
PDOSCC
N (%)
VC
N (%)
BSCC
N (%)
Total
N (%)

ALDH1
Negative/weak18 (38.3)12 (25.5)7 (14.9)10 (21.3)47 (100)0.021
Strong2 (12.4)5 (31.3)0 (0)9 (56.3)16 (100)

Notch1
Negative/weak9 (25.0)10 (27.8)4 (11.1)13 (36.1)36 (100)0.555
Strong11 (40.7)7 (26.0)3 (11.1)6 (22.2)27 (100)

WDOSCC, well-differentiated oral squamous cell carcinoma; PDOSCC, poorly differentiated squamous cell carcinoma; VC, verrucous carcinoma; BSCC, basaloid squamous cell carcinoma; N, number of tumors. Analysis by chi-square test.  < 0.05 was considered statistically significant.