Prognostic Implications of ALDH1 and Notch1 in Different Subtypes of Oral Cancer

Table 5

Univariate analysis for overall survival and disease-free survival in 63 patients with subtypes of oral cancer.

Variable	Overall survival		p	Disease-free survival		p
	HR	CI (95%)		HR	CI (95%)
Histologic grade
WDOSCC + VC(0)	4.546	[1.717; 12.036]	0.002	3.908	[1.446; 10.562]	0.007
PDOSCC + BSCC(1)
Lymph node (pN)
No (0)	2.250	[0.989; 5.115]	0.053	2.892	[1.094; 7.645]	0.032
Yes (1)
ALDH1						—
Negative/weak (0)	2.176	[1.009; 4.696]	0.047	—	—
Strong(1)

WDOSCC, well-differentiated oral squamous cell carcinoma; VC, verrucous carcinoma; PDOSCC, poorly differentiated squamous cell carcinoma; BSCC, basaloid squamous cell carcinoma; HR, hazard ratio; CI, confidence interval; value obtained by Cox test.  < 0.05 was considered statistically significant. The values highlighted in bold show that they were statistically significant.