Correlates of Long-Term Survival of Patients with pN+ Esophageal Squamous Cell Carcinoma after Esophagectomy

Table 4

Factors associated with DFS and LRFS on multivariate COX analysis.

Factors	DFS		LRFS
	HR (95% CI)		HR (95% CI)
Site of lesion
Upper	1.045 (0.685–1.596)	0.838	1.074 (0.628–1.836)	0.795
Middle	1.373 (1.062–1.776)	0.016	1.406 (1.020–1.938)	0.038
Lower	1		1
pTNM
IIb	1		1
IIIa	1.311 (0.884–1.944)	0.178	0.876 (0.571–1.343)	0.543
IIIb	1.873 (1.224–2.866)	0.004	1.300 (0.814–2.078)	0.272
IIIc	2.600 (1.637–4.129)	<0.001	1.870 (1.115–3.135)	0.018
Adjuvant therapy
No	1		1
POCT	0.656 (0.517–0.833)	<0.001	0.840 (0.627–1.126)	0.244
PORT	0.604 (0.426–0.857)	0.005	0.490 (0.301–0.797)	0.004
POCRT	0.388 (0.258–0.583)	<0.001	0.333 (0.190–0.584)	<0.001