Research Article
Clinical Characteristics and Prognostic Analysis of Multiple Myeloma with Extramedullary Disease: A SEER-Based Study
Table 3
Univariate Cox proportional regression analysis of myeloma-specific survival and overall survival.
| | | Myeloma-specific survival | Overall survival | | | Hazard ratio | 95% CI | value | Hazard ratio | 95% CI | value |
| Age at MM diagnosis (years) | | | | | | | | <60 | 1 | Reference | | 1 | Reference | | ≥60 | 1.786 | 1.096–2.912 | 0.02 | 1.9 | 1.21–2.984 | 0.005 |
| Gender | | | | | | | | Female | 1 | Reference | | 1 | Reference | | Male | 1.102 | 0.696–1.745 | 0.679 | 1.036 | 0.680–1.579 | 0.868 |
| Race | | | | | | | | Black | 1 | Reference | | 1 | Reference | | White | 0.777 | 0.404–1.493 | 0.448 | 0.808 | 0.443–1.471 | 0.485 | Others | 1.32 | 0.545–3.197 | 0.539 | 1.256 | 0.549–2.874 | 0.59 |
| EMD site | | | | | | | | EMD-B | 1 | Reference | | 1 | Reference | | EMD-S | 1.646 | 1.036–2.615 | 0.035 | 1.537 | 1.005–2.352 | 0.048 |
| Interval (month) | | | | | | | | 0 | 1 | Reference | | 1 | Reference | | ≤24 | 1.951 | 1.048–4.016 | 0.039 | 1.658 | 1.004–3.074 | 0.048 | >24 | 0.554 | 0.274–0.98 | 0.047 | 0.423 | 0.229–0.780 | 0.006 |
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