Clinical Characteristics and Prognostic Analysis of Multiple Myeloma with Extramedullary Disease: A SEER-Based Study

Table 4

Multivariate Cox proportional regression analysis of myeloma-specific survival and overall survival.

		Myeloma-specific survival			Overall survival
		Hazard ratio (adjusted)	95% CI	value	Hazard ratio (adjusted)	95% CI	value
Age at MM diagnosis (years)	<60	1	Reference		1	Reference
	≥60	1.538	1.002–2.556	0.047	1.558	1.014–2.493	0.046
Gender
	Female	1	Reference		1	Reference
	Male	0.983	0.598–1.616	0.947	0.897	0.57–1.409	0.636
Race
	Black	1	Reference		1	Reference
	White	0.682	0.342–1.359	0.277	0.706	0.375–1.327	0.279
	Others	1.242	0.507–3.04	0.635	1.154	0.499–2.672	0.737
EMD site
	EMD-B	1	Reference		1	Reference
	EMD-S	1.844	1.117–3.042	0.017	1.853	1.166–2.942	0.009
Interval (month)
	0	1	Reference		1	Reference
	≤24	1.885	1.175–3.346	0.042	1.33	1.119–2.529	0.036
	>24	0.435	0.202–0.935	0.034	0.33	0.168–0.648	0.001