Research Article

Pretreatment 18F-FDG PET/CT Imaging Predicts the KRAS/NRAS/BRAF Gene Mutational Status in Colorectal Cancer

Table 1

Patient and tumor characteristics.

CharacteristicsCases (%)

Patients, n85

Gender
 Male51 (60%)
 Female34 (40%)

Age, years
 Mean ± SD59.27 ± 11.56
 Range26–79

BMI
 Mean ± SD21.97 ± 3.21
 Range15.43–33.87

Tumor location
 Left hemicolon33 (38.9%)
 Right hemicolon22 (25.9%)
 Rectum30 (35.2%)

Histologic type
 Nonmucinous adenocarcinoma83 (97.6%)
 Mucinous adenocarcinoma2 (2.4%)

Differentiation
 Well/moderate74 (87.1%)
 Poor11 (12.9%)

UICC-TNM stage
 I/II33 (38.8%)
 III/IV52 (61.2%)

T-category
 Tis, T1, T24 (4.7%)
 T3, T481 (95.3%)

N-category
 Positive67 (78.8%)
 Negative18 (21.2%)

M-category
 Positive56 (65.9%)
 Negative29 (34.1%)

Tumor size, mm
 Mean ± SD49.2 ± 28.17
 Range10–180

Mutational status
 KRAS/NRAS/BRAF mutated46 (54.1%)
 Wild-type39 (45.9%)

UICC, Union for International Cancer Control.