The Analysis of bcl-2 in Association with p53 and Ki-67 in Triple Negative Breast Cancer and Other Molecular Subtypes in Ghana

Table 5

Correlations of bcl-2 with molecular subtypes, apoptotic biomarkers, and clinicopathologic characteristics.

bcl-2
	% Positive	Cramer’s V	Pearson’s Chi^2	Sig. ()
Molecular subtypes
Luminal A	45.2	0.005	0.004	0.950
Luminal B	75	0.204	6.629	0.015
HER2 positive	53.8	0.082	1.063	0.303
Triple negative	36	0.174	4.856	0.038
Apoptotic biomarkers
p53	44.4	0.124	2.593	0.107
Ki-67 mild (low); Moderate; High (severe)	54.1; 18.9; 27	0.121	2.583	0.275
Clinicopathologic characteristics
Histol. grade I; II; III	38.5; 44.7; 34.3	0.099	1.284	0.526
Lymphovascular invasion	59.3	0.148	1.187	0.276