The Clinical Significance and Potential Molecular Mechanism of Upregulated CDC28 Protein Kinase Regulatory Subunit 1B in Osteosarcoma

Figure 7

Regulon activity of proliferating osteoblastic osteosarcoma (OS) cells. (a) UMAP map of 4 clusters of proliferating osteoblastic OS cells based on regulon activity. (b) Binarized regulon activity scores for MYC regulon potentially regulated CKS1B on uniform manifold approximation and projection (UMAP) map (dark green dots). (c) Binarized regulon activity scores for top regulon CREB3L1 on UMAP map (dark green dots). (d) Binarized regulon activity scores for top regulon OSR2 on UMAP map (dark green dots). (e) Binarized regulon activity scores for top regulon ZNF460 on UMAP map (dark green dots).

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