In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion

Figure 1

miRNA-296-3p levels and the effects of miRNA-296-3p mimic on HCC proliferation. (a) The expression level of miRNA-296-3p in normal human hepatocytes (HL-7702) and HCC cell lines (Huh-7, MHCC97-H, HepG2, and SMMC-7721) (qRT-PCR). vs. HL-7702. n = 6. (b) The Huh-7 and HepG2 cells were transfected with miRNA-296-3p mimics and a negative control (NC mimic). The qRT-PCR assay was used to determine the miRNA-296-3p expression levels in each group. (c) CCK-8 kits evaluated cell proliferation and (d) cell growth and colony formation assays in Huh-7 and HepG2 transfected with NC mimic and miRNA-296-3p mimic. Values were mean ± SE, vs. NC mimic. n = 3 per group.

(a)

(b)

(c)

(d)