Research Article

Upregulated Expression of CYBRD1 Predicts Poor Prognosis of Patients with Ovarian Cancer

Table 1

Characteristics of patients with ovarian serous cystadenocarcinoma obtained from TCGA data.

CharacteristicLow expression of CYBRD1High expression of CYBRD1

N188188

FIGO stage, n (%)0.951
 Stage I1 (0.3%)0 (0%)
 Stage II11 (2.9%)11 (2.9%)
 Stage III145 (38.9%)148 (39.7%)
 Stage IV30 (8%)27 (7.2%)

Primary therapy outcome, n (%)0.017
 PD12 (3.9%)15 (4.9%)
 SD7 (2.3%)15 (4.9%)
 PR17 (5.6%)26 (8.5%)
 CR124 (40.7%)89 (29.2%)

Age, n (%)1.000
 ≤60104 (27.7%)103 (27.4%)
 >6084 (22.3%)85 (22.6%)

Anatomic neoplasm subdivision, n (%)0.201
 Unilateral57 (16.1%)44 (12.4%)
 Bilateral122 (34.5%)131 (37%)

Venous invasion, n (%)0.623
 No25 (24.3%)15 (14.6%)
 Yes35 (34%)28 (27.2%)

Lymphatic invasion, n (%)0.845
 No27 (18.2%)21 (14.2%)
 Yes53 (35.8%)47 (31.8%)

Tumor residual, n (%)0.410
 NRD36 (10.8%)30 (9%)
 RD128 (38.4%)139 (41.7%)

OS event, n (%)0.112
 Alive81 (21.5%)65 (17.3%)
 Dead107 (28.5%)123 (32.7%)

DSS event, n (%)0.074
 Alive85 (24.2%)67 (19.1%)
 Dead91 (25.9%)108 (30.8%)

Age, median (IQR)58 (50, 67)59 (51, 68)0.627