Research Article
Long-Term Survival of Patients with Metastatic Non-Small-Cell Lung Cancer over Five Decades
Table 2
Percentage survival at two and five years by prognostic factors.
| | 2yOS | 5yOS | % | 95% CI | % | 95% CI |
| Entire cohort | 8.0 | (7.9–8.2) | 2.1 | (2.0–2.1) |
| Age | <67 | 9.5 | (9.3–9.6) | 2.7 | (2.6–2.7) | ≧67 | 6.6 | (6.5–6.7) | 1.5 | (1.5–1.6) |
| Sex | Male | 6.3 | (6.1–6.4) | 1.6 | (1.5–1.7) | Female | 10.5 | (10.3–10.7) | 2.8 | (2.7–2.9) |
| Race | White | 7.5 | (7.4–7.7) | 2 | (1.9–2.0) | Black | 7.2 | (6.9–7.5) | 1.8 | (1.7–2.0) | American Indian/Alaska native | 8.6 | (7.0–10.4) | 1.5 | (0.8–2.6) | Asian/Pacific Islander | 15.1 | (14.5–15.6) | 4.1 | (3.7–4.4) | Unk/oth | 23.1 | (17.6–29.1) | 15.1 | (9.8–21.5) |
| Marital status | Single | 7.0 | (6.9–7.2) | 1.8 | (1.7–1.9) | Married | 8.7 | (8.6–8.9) | 2.3 | (2.2–2.4) |
| Histology | Adenocarcinoma | 10.8 | (10.6–11) | 2.7 | (2.6–2.8) | Lung carcinoma NOS | 5.1 | (5.0–5.3) | 1.3 | (1.3–1.4) | Squamous cell carcinoma | 6.2 | (6.0–6.4) | 1.8 | (1.7–1.9) | Small-cell carcinoma | 4.4 | (4.3–4.6) | 1.3 | (1.2–1.4) |
| Grade | Well differentiated | 18.6 | (17.6–19.7) | 6.3 | (5.6–7.0) | Moderately differentiated | 13.2 | (12.8–13.7) | 3.8 | (3.5–4.1) | Poorly differentiated | 7.1 | (6.9–7.3) | 2.0 | (1.9–2.1) | Undifferentiated | 4.5 | (4.1–4.8) | 1.3 | (1.1–1.5) |
| Year of diagnosis | 1973–79 | 3.1 | (2.9–3.4) | 0.7 | (0.6–0.9) | 1980–89 | 3.5 | (3.3–3.7) | 0.9 | (0.8–1.0) | 1990–99 | 4.5 | (4.3–4.7) | 1.1 | (1.0–1.2) | 2000–09 | 8.4 | (8.3–8.6) | 2.1 | (2.0–2.2) | 2010–15 | 12.6 | (12.3–12.9) | 3.7 | (3.5–3.9) |
| Treatment | None | 4.5 | (4.3–4.6) | 1.6 | (1.5–1.7) | Chemotherapy only | 14.9 | (14.6–15.2) | 3.3 | (3.1–3.5) | Radiotherapy (RT) only | 4.0 | (3.9–4.2) | 1.0 | (1.0–1.1) | Chemotherapy + RT | 11.7 | (11.5–12) | 2.9 | (2.8–3.1) |
| Income | <mediana | 7.2 | (7.0–7.4) | 1.9 | (1.8–2.0) | ≧mediana | 8.5 | (8.4–8.7) | 2.2 | (2.1–2.3) |
|
|
2yOS: two-year overall survival. 5yOS: five-year overall survival. CI: confidence interval. NOS: non-other specified. Ca: carcinoma. aAnnual county median in 2010 of $52,595.
|