Research Article
MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma
Table 1
Clinical and histopathologic characteristics of the early-stage oral squamous cell carcinoma patients included in this study.
| | S only | S + ND | S + IR | S + ND/IR |
| Patients | n = 551 | n = 164 | n = 76 | n = 45 |
| Age | Mean (range) | 66 (21–97) | 61 (25–87) | 65 (24–90) | 58 (35–80) |
| Gender | Female | 218 (40%) | 84 (51%) | 24 (32%) | 21 (47%) | Male | 333 (60%) | 80 (49%) | 52 (68%) | 24 (53%) |
| Race/Ethnicity | White non-Hispanic | 383 (70%) | 92 (56%) | 30 (39%) | 22 (49%) | White hispanic | 80 (15%) | 15 (9%) | 9 (12%) | 9 (20%) | Black non-Hispanic | 22 (4%) | 4 (2%) | 1 (1%) | 7 (6%) | Black hispanic | 5 (1%) | 0 (0%) | 0 (0%) | 0 (0%) | Asian | 52 (9%) | 34 (21%) | 27 (36%) | 5 (11%) | Unknown | 9 (2%) | 19 (12%) | 9 (12%) | 2 (4%) |
| TNM Stage | Stage I | 428 (78%) | 81 (49%) | 40 (53%) | 17 (38%) | Stage II | 123 (22%) | 83 (51%) | 36 (47%) | 28 (62%) | Histologic grading | | | | | Well-differentiated | 291 (53%) | 76 (46%) | 29 (38%) | 8 (18%) | Moderately/poorly differentiated | 260 (47%) | 88 (54%) | 47 (62%) | 37 (82%) |
| Smoking Status | Never | 163 (30%) | 64 (39%) | 2 (3%) | 17 (38%) | Past | 72 (13%) | 39 (24%) | 9 (12%) | 7 (16%) | Current | 54 (48%) | 12 (7%) | 5 (7%) | 6 (13%) | Unknown | 262 (48%) | 49 (30%) | 60 (79%) | 15 (33%) |
| Alcohol Abuse | Never | 201 (36%) | 80 (49%) | 4 (5%) | 22 (49%) | Past | 32 (6%) | 14 (9%) | 6 (8%) | 0 (0%) | Current | 56 (10%) | 21 (13%) | 6 (8%) | 8 (18%) | Unknown | 262 (48%) | 49 (30%) | 60 (79%) | 15 (33%) |
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