Research Article

MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma

Table 1

Clinical and histopathologic characteristics of the early-stage oral squamous cell carcinoma patients included in this study.

S onlyS + NDS + IRS + ND/IR

Patientsn = 551n = 164n = 76n = 45

Age
Mean (range)66 (21–97)61 (25–87)65 (24–90)58 (35–80)

Gender
Female218 (40%)84 (51%)24 (32%)21 (47%)
Male333 (60%)80 (49%)52 (68%)24 (53%)

Race/Ethnicity
White non-Hispanic383 (70%)92 (56%)30 (39%)22 (49%)
White hispanic80 (15%)15 (9%)9 (12%)9 (20%)
Black non-Hispanic22 (4%)4 (2%)1 (1%)7 (6%)
Black hispanic5 (1%)0 (0%)0 (0%)0 (0%)
Asian52 (9%)34 (21%)27 (36%)5 (11%)
Unknown9 (2%)19 (12%)9 (12%)2 (4%)

TNM Stage
Stage I428 (78%)81 (49%)40 (53%)17 (38%)
Stage II123 (22%)83 (51%)36 (47%)28 (62%)
Histologic grading
Well-differentiated291 (53%)76 (46%)29 (38%)8 (18%)
Moderately/poorly differentiated260 (47%)88 (54%)47 (62%)37 (82%)

Smoking Status
Never163 (30%)64 (39%)2 (3%)17 (38%)
Past72 (13%)39 (24%)9 (12%)7 (16%)
Current54 (48%)12 (7%)5 (7%)6 (13%)
Unknown262 (48%)49 (30%)60 (79%)15 (33%)

Alcohol Abuse
Never201 (36%)80 (49%)4 (5%)22 (49%)
Past32 (6%)14 (9%)6 (8%)0 (0%)
Current56 (10%)21 (13%)6 (8%)8 (18%)
Unknown262 (48%)49 (30%)60 (79%)15 (33%)