MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma

Table 2

The efficacy of various treatment regimens in oral squamous cell carcinoma patients stratified into high (risk score ≥0) versus low-risk (risk score <0) using the microRNA-based prognostic model; surgery (S) only, surgery with neck dissection (S + ND), surgery with irradiation (S + IR), and surgery with neck dissection and irradiation (S + ND/IR).

Treatment	Risk category	Median time-to-recurrence	Median time-to-death	Cancer death (%)	5-year survival (%)
S	High risk (≥0)	26 (months)	50 (months)	54	46
	Low risk (<0)	≥60	≥60	11	89
S + ND	High risk	≥60	≥60	25	75
	Low risk	≥60	≥60	26	74
S + IR	High risk	41	43	56	44
	Low risk	33	≥60	49	51
S + ND/IR	High risk	7	≥60	38	62
	Low risk	≥60	≥60	34	66

when compared with the same risk strata of S only.