MicroRNA-Based Cancer Mortality Risk Scoring System and hTERT Expression in Early-Stage Oral Squamous Cell Carcinoma

Table 4

The ΔΔCt and the fold change in the expression levels of Rac1, Cdc42, and hTERT in four sub-risk strata compared to healthy controls. The hTERT expression levels significantly correlated with the risk scores.

Sub-risk strata	Risk score	ΔΔCt			Fold change
		Rac1	Cdc42	hTERT	Rac1	Cdc42	hTERT
Highest risk	≥2	3.22	1.05	4.55	8.32	1.07	22.43
Moderately high risk	1 to <2	2.95	0.88	3.86	6.71	0.84	13.53
Moderately low risk	0 to <1	2.77	0.23	3.61	5.81	0.17	11.17
Low risk	<0	2.00	0.21	3.42	3.01	0.16	9.78
Healthy controls	—	Reference	Reference	Reference	Reference	Reference	Reference

when compared with the healthy controls.