Research Article

Long Noncoding RNA MALAT1 Interacts with miR-124-3p to Modulate Osteosarcoma Progression by Targeting SphK1

Figure 2

MALAT1 is associated with OS cells proliferation and migration. (a, b) CCK-8 assay showed that knockdown of MALAT1 decreased the cell viability of both MG63 and U2OS cells for up to 4 days, compared with the si-NC group. (c–e) Cell migration in MG63 and U2OS cells transfected with si-MALAT1 or si-NC was detected by scratch assay and is shown both pictorially and graphically. Compared to the si-NC group, knockdown of MALAT1 reduced the relative migration distance in both MG63 and U2OS cells for up to 48 hours. and .
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