miR-23b-3p Inhibits the Oncogenicity of Colon Adenocarcinoma by Directly Targeting NFE2L3

Figure 2

Overexpression of miR-23b-3p inhibits the proliferation, migration, and invasion of COAD cells. (a) Tumor cells were transfected with miR-23b-3p mimics or NC; qRT-PCR analysis was performed to determine transfection efficiency. (b–d) CCK-8, colony formation, and EdU assays were used to detect proliferation of COAD cells. (e, f) Transwell assay was performed to evaluate the migration and invasion capacity of COAD cells. (g) Flow cytometry was used to evaluate cell apoptosis. The results are presented expressed as the mean ± SD from three independent experiments. vs. NC.

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