Identification of a Nomogram from Ferroptosis-Related Long Noncoding RNAs Signature to Analyze Overall Survival in Patients with Bladder Cancer

Table 3

Univariate and multivariate Cox regression analysis of the association between clinicopathological indexes (including risk score) and overall survival of BC patients in the training, testing, and overall sets.

Variable

Overall set

Training set

Testing set

Univariate

Multivariate

Univariate

Multivariate

Univariate

Multivariate

HR (95% CI)

HR (95% CI)

HR (95% CI)

HR (95% CI)

HR (95% CI)

HR (95% CI)

Age

1.029 (1.001–1.057)

0.045

1.026 (0.998–1.055)

0.071

1.008 (0.971–1.047)

0.674

1.021 (0.976–1.068)

0.365

1.046 (1.003–1.090)

0.035

1.011 (0.965–1.059)

0.652

Gender

0.616 (0.352–1.078)

0.090

0.729 (0.402–1.321)

0.297

0.623 (0.299–1.296)

0.206

0.745 (0.340–1.635)

0.463

0.687 (0.287–1.648)

0.401

1.070 (0.415–2.761)

0.888

Stage

1.863 (1.293–2.683)

<0.001

1.103 (0.514–2.364)

0.801

1.869 (1.157–3.018)

0.011

1.297 (0.478–3.519)

0.610

1.864 (1.070–3.250)

0.028

0.541 (0.162–1.808)

0.318

T stage

1.769 (1.193–2.622)

0.005

1.436 (0.830–2.485)

0.195

1.410 (0.862–2.308)

0.171

1.019 (0.509–2.041)

0.958

2.499 (1.300–4.804)

0.006

3.514 (1.319–9.358)

0.012

N stage

1.573 (1.196–2.070)

0.001

1.304 (0.763–2.230)

0.332

1.656 (1.103–2.488)

0.015

1.281 (0.574–2.860)

0.545

1.551 (1.058–2.275)

0.025

2.008 (0.902–4.472)

0.088

M stage

2.167 (0.779–6.025)

0.138

1.009 (0.319–3.194)

0.987

4.857 (1.108–21.287)

0.036

1.783 (0.372–8.553)

0.470

1.392 (0.326–5.949)

0.655

0.322 (0.053–1.946)

0.217

Risk score

1.414 (1.272–1.573)

<0.001

1.388 (1.228–1.568)

<0.001

1.350 (1.190–1.532)

<0.001

1.350 (1.156–1.578)

<0.001

1.507 (1.193–1.904)

<0.001

1.446 (1.088–1.924)

0.011

BC, bladder cancer; HR, hazard ratio; CI, confidence interval.