LncRNA MALAT1 Accelerates Cervical Carcinoma Proliferation by Suppressing miR-124 Expression in Cervical Tumor Cells

Figure 1

MALAT1 is negatively related to miR-124 expression in cervical tumor tissues and cell lines. (a) Complementary pairing sequence of LncRNA MALAT1 and miR-124 was evaluated by RNA22 v2 microRNA target detection (https://cm.jefferson.edu/rna22/Interactive). (b, c) LncRNA MALAT1 and miR-124 levels were detected by real-time PCR in paracarcinoma tissues and carcinoma tissues of 15 cervical tumor patients, n = 15, and . (d, e) LncRNA MALAT1 and miR-124 levels were detected by real-time PCR in End1/E6E, Hela, C-33A, Caski, and SiHa cell lines, n = 5 in each batches, compared with the End1/E6E group. (f–h) Linear analysis was performed to detect the relationship between LncRNA MALAT1 and miR-124 levels in tissues from 15 cervical cancer patients and 7 tumor-bearing nude mice.

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