Research Article
ACE2 Is a Prognostic Biomarker and Associated with Immune Infiltration in Kidney Renal Clear Cell Carcinoma: Implication for COVID-19
Table 1
Correlation of ACE2 expression and the overall survival of KIRC with different clinicopathological factors (Kaplan–Meier plotter).
| Pathological parameters | Case number | Hazard radio | value |
| Stage status | | | | 1 | 398 | 0.57 (0.31–1.05) | 0.069 | 2 | 184 | 0.29 (0.1–0.89) | 0.021 | 3 | 332 | 0.34 (0.19–0.6) | 0.00011 | 4 | 188 | 0.26 (0.15–0.45) | 2.5e−7 | Gender | | | | Female | 284 | 0.41 (0.25–0.68) | 0.00038 | Male | 948 | 0.35 (0.24–0.52) | 2e−8 | White | 690 | 0.36 (0.26–0.5) | 3.2e−11 | Asian | 8 | NA | NA | Black/African-American | 111 | 2.81 (0.59–13.37) | 0.18 | Tumor grade | | | | 1 | 14 | NA | NA | 2 | 340 | 0.5 (0.28–0.92) | 0.022 | 3 | 585 | 0.38 (0.24–0.61) | 2.2e−5 | 4 | 174 | 0.42 (0.23–0.77) | 0.0039 | Mutation burden | | | | high | 246 | 0.43 (0.25–0.76) | 0.0027 | low | 437 | 0.34 (0.16–0.75) | 0.0051 |
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