BCL-2 (-938C>A), BAX (-248G>A), and HER2 Ile655Val Polymorphisms and Breast Cancer Risk in Indian Population
Table 3
Genotype distribution, allele frequency, and association analysis of BAX(-248G>A) polymorphism and risk of breast cancer under different genetic models.
Genotype/allele
Cases (n = 117)
Control (n = 104)
Odd ratio (95% CI)
value
GG
93 (79.48%)
81 (77.88%)
Ref
Ref
AG
20 (17.09%)
19 (18.26%)
0.916 (0.457–1.837)
0.806
AA
4 (3.41%)
4 (3.84%)
0.871 (0.211–3.594)
0.848
value -0.956
Recessive model
AA
4
4
0.88 (0.21–3.63)
0.865
AG + GG
113
100
Dominant model
AG + AA
24
23
0.90 (0.47 to 1.73)
0.771
GG
93
81
Codominant model
AG
20
19
0.92 (0.46–1.84)
0.819
GG + AA
97
85
Allele
G
206 (88.03%)
181 (87.02%)
0.91 (0.51 to 1.60)
0.747
A
28 (11.97%)
27 (12.98%)
OR: odds ratio, CI: confidence interval, and n: number of samples.
