CEP55 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma and Is Correlated with Poor Prognosis
Table 1
CEP55 expression and clinicopathologic variables in ESCC patients.
Variable
CEP55 expression
Cases (n = 241)
Low (n = 99, percent)
High (n = 142, percent)
valuea
Ageb (years)
0.155
≤58
128
58 (45.3)
70 (54.7)
>58
113
41 (36.3)
72 (63.7)
Sex
0.739
Male
63
27 (142.9)
36 (57.1)
Female
178
72 (40.4)
106 (59.60
Tumor location
0.639
Upper ESCC
12
4 (33.3)
8 (66.7)
Middle ESCC
165
71 (43.0)
94 (57.0)
Lower ESCC
64
24 (37.5)
40 (62.5)
Histological grade
0.273
Grade 1
58
29 (50.0)
29 (50.0)
Grade 2
155
60 (38.7)
95 (61.3)
Grade 2
64
10 (35.7)
18 (64.3)
pT status
0.869
pT 1
6
3 (50.0)
3 (50.0)
pT 2
54
20 (37.00)
34 (63.0)
pT 3
178
75 (42.1)
103 (57.9)
pT 4
3
1 (33.3)
2 (66.7)
N categories
0.024
Negative
130
62 (47.7)
68 (52.3)
Positive
111
37 (33.3)
74 (66.7)
TNM stage
0.046
Stage I
9
5 (55.6)
4 (44.4)
Stage II
138
64 (46.4)
74 (53.6)
Stage III
93
29 (31.2)
64 (68.8)
aProbability value of <0.05 indicates statistical significance. Probability values are calculated by Pearson’s c2 test. bAge is divided according to the median age of 58 years. cThe grading and histopathology stage of ESCC specimens are based on the World Health Organization (WHO) classification published in 2009.
