Research Article
CEP55 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma and Is Correlated with Poor Prognosis
Table 2
Analysis of risk factors for overall survival in ESCC patients.
| | Variable | Univariate analysis | Multivariate analysis | | HR (95% CI) | value | HR (95% CI) | value |
| | Age b (years) | | 0.779 | | | | ≤58 | 1.000 | | | | | >58 | 0.951 (0.671–1.349) | | | |
| | Sex | | 0.162 | | | | Male | 1.000 | | | | | Female | 1.340 (0.889–2.020) | | | |
| | Tumor location | | 0.325 | | | | Upper ESCC | 1.000 | | | | | Middle ESCC | 1.628 (0.777–1.536) | | | | | Lower ESCC | 0.968 (0.644–1.454) | | | |
| | Histological grade | | 0.130 | | | | Grade 1 | 1.000 | | | | | Grade 2 | 1.007 (0.660–1.536) | | | | | Grade 2 | 1.656 (0.931–2.948) | | | |
| | pT status | | <0.001 | | <0.001 | | pT 1 | 1.000 | | 1.000 | | | pT 2 | 1.596 (0.377–6.760) | | 1.726 (0.407–7.324) | | | pT 3 | 2.272 (0.559–9.231) | | 2.308 (0.567–9.403) | | | pT 4 | 64.653 (9.871–423.451) | | 91.578 (13.736–610.554) | |
| | N categories | | <0.001 | | <0.001 | | Negative | 1.000 | | 1.000 | | | Positive | 3.457 (2.381–5.018) | | 3.280 (2.245–4.791) | |
| | TNM stage | | <0.001 | | | | Stage I | 1.000 | | | | | Stage II | 1.047 (0.326–3.357) | | | | | Stage III | 4.158 (1.304–13.261) | | | |
| | CEP55 expression | | <0.001 | | 0.009 | | Low | 1.000 | | 1.000 | | | High | 1.960 (1.340–2.865) | | 1.669 (1.136–2.453) | |
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