Research Article
CEP55 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma and Is Correlated with Poor Prognosis
Table 3
Analysis for risk factors for disease-free survival in ESCC patients.
| | Variable | Univariate analysis | Multivariate analysis | | HR (95% CI) | value | HR (95% CI) | value |
| | Age b (years) | | 0.824 | | | | ≤58 | 1.000 | | | | | >58 | 0.961 (0.678–1.363) | | | |
| | Sex | | 0.218 | | | | Male | 1.000 | | | | | Female | 1.294 (0.859–1.951) | | | |
| | Tumor location | | 0.348 | | | | Upper ESCC | 1.000 | | | | | Middle ESCC | 1.663 (0.793–3.487) | | | | | Lower ESCC | 1.015 (0.676–1.525) | | | |
| | Histological grade | | 0.076 | | | | Grade 1 | 1.000 | | | | | Grade 2 | 1.020 (0.669–1.555) | | | | | Grade 2 | 1.775 (0.998–3.156) | | | |
| | pT status | | <0.001 | | <0.001 | | pT 1 | 1.000 | | 1.000 | | | pT 2 | 1.439 (0.340–6.091) | | 1.444 (0.340–6.120) | | | pT 3 | 1.983 (0.488–8.051) | | 1.866 (0.459–7.596) | | | pT 4 | 30.493 (4.752–195.655) | | 37.674 (5.823–243.733) | |
| | N categories | | <0.001 | | <0.001 | | Negative | 1.000 | | 1.000 | | | Positive | 3.319 (2.287–4.815) | | 3.115 (2.135–4.545) | |
| | TNM stage | | <0.001 | | | | Stage I | 1.000 | | | | | Stage II | 1.066 (0.332–3.419) | | | | | Stage III | 3.952 (1.241–12.586) | | | |
| | CEP55 expression | | 0.001 | | 0.015 | | Low | 1.000 | | 1.000 | | | High | 1.894 (1.296–2.768) | | 1.612 (1.097–2.369) | |
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