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lncRNA | Cancer type | Role in cancer | Molecular mechanism | Refs |
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NIFK-AS1 | Endometrial cancer | Inhibit | Sponge miR-146a, inhibits M2-like polarization of macrophages | [53] |
LINC01315 | Colorectal cancer | Promote | Sponge miR-205-3p, upregulates PRKAA1 | [54] |
Oral squamous cell carcinoma | Inhibit | Sponge miR-211, upregulates DLG3, activates Hippo signaling | [55] |
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LINC00667 | Colorectal cancer | Promote | Sponge miR-449b-5p, activated by YY1 | [56] |
NSCLC | Recruits EIF4A3 to stabilize VEGFA | [57] |
Cholangiocarcinoma | Sponge miR-200c-3p, promotes PDK1, activated by YY1 | [58] |
Glioma | USF1/linc00667/miR-429/ALDH1A1 axis | [59] |
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ASB16-AS1 | Gastric cancer | Promote | Sponge miR-3918 and miR-4676-3p, cooperates with ATM, induces TRIM37 phosphorylation | [60] |
HCC | Regulates miR-1827/FZD4 axis, activates wnt/β-catenin pathway | [61] |
Osteosarcoma | Sponge miR-760, upregulates HDGF | [62] |
Cervical cancer | miR-1305/wnt/β-catenin axis | [63] |
Glioma | Affects EMT signaling pathway | [64] |
Adrenocortical carcinoma | Inhibit | Promotes ubiquitination of HuR | [65] |
Clear cell renal cell carcinoma | miR-185-5p-miR-214-3p-LARP1 pathway | [66] |
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PINK1-AS | Gastric cancer | Promote | Sponge miR-200a, upregulates Gαi1 | [67] |
ZSCAN16-AS1 | HCC | Promote | Regulates miR-181c-5p/SPAG9 axis, activates the JNK pathway | [68] |
SOCS2-AS1 | Prostate cancer | Promote | Inhibits apoptosis pathway, promotes androgen signaling by modulating the epigenetic control for AR target genes | [69] |
Colorectal cancer | Inhibit | Sponge miR-1264, upregulates SOCS2 | [70] |
Endometrial cancer | Regulates AURKA degradation | [71] |
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TINCR | Breast cancer | Promote | Recruits DNMT1 and increases the methylation and suppresses the transcriptional expression of miR-503-5p, sponge miR-503-5p, and upregulates EGFR, stimulates JAK2-STAT3 signaling downstream from EGFR | [45] |
Guides STAU1 to OAS1 mRNA to mediate its stability | [72] |
HCC | Interacts with TCPTP, activates STAT3 signaling | [73] |
Laryngeal squamous cell carcinoma | Inhibit | miR-210/BTG2 pathway | [74] |
Melanoma | Prevents ATF4 translation | [75] |
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