Development of a Prognostic Model Based on the Identification of EMT-Related lncRNAs in Triple-Negative Breast Cancer

Table 1

lncRNAs in cancers.

lncRNA	Cancer type	Role in cancer	Molecular mechanism	Refs
NIFK-AS1	Endometrial cancer	Inhibit	Sponge miR-146a, inhibits M2-like polarization of macrophages	[53]
LINC01315	Colorectal cancer	Promote	Sponge miR-205-3p, upregulates PRKAA1	[54]
	Oral squamous cell carcinoma	Inhibit	Sponge miR-211, upregulates DLG3, activates Hippo signaling	[55]
LINC00667	Colorectal cancer	Promote	Sponge miR-449b-5p, activated by YY1	[56]
	NSCLC		Recruits EIF4A3 to stabilize VEGFA	[57]
	Cholangiocarcinoma		Sponge miR-200c-3p, promotes PDK1, activated by YY1	[58]
	Glioma		USF1/linc00667/miR-429/ALDH1A1 axis	[59]
ASB16-AS1	Gastric cancer	Promote	Sponge miR-3918 and miR-4676-3p, cooperates with ATM, induces TRIM37 phosphorylation	[60]
	HCC		Regulates miR-1827/FZD4 axis, activates wnt/β-catenin pathway	[61]
	Osteosarcoma		Sponge miR-760, upregulates HDGF	[62]
	Cervical cancer		miR-1305/wnt/β-catenin axis	[63]
	Glioma		Affects EMT signaling pathway	[64]
	Adrenocortical carcinoma	Inhibit	Promotes ubiquitination of HuR	[65]
	Clear cell renal cell carcinoma		miR-185-5p-miR-214-3p-LARP1 pathway	[66]
PINK1-AS	Gastric cancer	Promote	Sponge miR-200a, upregulates Gαi1	[67]
ZSCAN16-AS1	HCC	Promote	Regulates miR-181c-5p/SPAG9 axis, activates the JNK pathway	[68]
SOCS2-AS1	Prostate cancer	Promote	Inhibits apoptosis pathway, promotes androgen signaling by modulating the epigenetic control for AR target genes	[69]
	Colorectal cancer	Inhibit	Sponge miR-1264, upregulates SOCS2	[70]
	Endometrial cancer		Regulates AURKA degradation	[71]
TINCR	Breast cancer	Promote	Recruits DNMT1 and increases the methylation and suppresses the transcriptional expression of miR-503-5p, sponge miR-503-5p, and upregulates EGFR, stimulates JAK2-STAT3 signaling downstream from EGFR	[45]
			Guides STAU1 to OAS1 mRNA to mediate its stability	[72]
	HCC		Interacts with TCPTP, activates STAT3 signaling	[73]
	Laryngeal squamous cell carcinoma	Inhibit	miR-210/BTG2 pathway	[74]
	Melanoma		Prevents ATF4 translation	[75]