Combining Intravoxel Incoherent Motion Diffusion Weighted Imaging and Texture Analysis for a Nomogram to Predict Early Treatment Response to Concurrent Chemoradiotherapy in Cervical Cancer Patients

Figure 1

Example of manually drawing ROIs for cervical cancer. IVIM-DWI measurement (b = 1200 s/mm²) (a); each radiologist drew ROI-1 (5 mm²) three times to get the values on the maps of ADC, D, , and f, respectively (b–e). Texture analysis, tumor segmentation in cervical cancer, and segmentation were performed on T2WI (f); by stacking up segmented ROIs slice-by-slice, VOI covering the entire tumor (g) was acquired. ROI: region of interest; IVIM-DWI: intravoxel incoherent motion diffusion weighted imaging; ADC: apparent diffusion coefficient; D: slow diffusion coefficient; : fast diffusion coefficient; f: perfusion-related diffusion fraction; T2WI: T2-weighted imaging; VOI: volume of interest.