Combining Intravoxel Incoherent Motion Diffusion Weighted Imaging and Texture Analysis for a Nomogram to Predict Early Treatment Response to Concurrent Chemoradiotherapy in Cervical Cancer Patients

Figure 4

(a) The fivefold cross-validation plot of the nomogram. Brier score = 0.060. C-index = 0.953. The 45° dashed line refers to the location of an ideal nomogram, with identical actual and predicted probabilities. The dotted line refers to the performance of the apparent nomogram, and the solid line refers to the performance of the nomogram with bootstrap correction. (b) Decision curve analysis (DCA). y-axis indicates the net benefit, and x-axis indicates the threshold probability. Compared with the IVIM-DWI (red line), TA (green line), treat-all strategy (gray line), and treat-none strategy (horizontal black line), the combination of IVIM-DWI combined with TA nomogram (blue line) achieves the highest net benefit. IVIM-DWI: intravoxel incoherent motion diffusion weighted imaging; TA: texture analysis.

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