Nrf3 Promotes 5-FU Resistance in Colorectal Cancer Cells via the NF-κB/BCL-2 Signaling Pathway In Vitro and In Vivo

Table 2

Correlation between Nrf3 expression and clinicopathologic factors.

Variables	Cases	NRF3
		+	−
Age				0.294
<60	40	21	19
≥60	57	36	21
Sex				0.501
Male	62	38	24
Female	35	19	16
Smoke				0.178
+	36	18	18
−	61	39	22
Tumor differentiation				0.675
Low	13	8	5
Median	55	28	27
High	29	21	8
TNM classification				0.798
I	5	2	3
II	48	29	19
III	30	17	13
IV	14	9	5
Lymph node metastasis				0.528
+	40	22	18
−	57	35	22
Distant metastasis				0.873
+	14	9	5
−	83	48	35