Research Article
Role of miRNA-495 and NRXN-1 and CNTN-1 mRNA Expression and Its Prognostic Importance in Breast Cancer Patients
Table 3
Association of NRXN-1 mRNA expression in breast cancer cases with different clinicopathological features.
| Variables | NRXN-1 mRNA expression | value | Mean | SD |
| Relative expression | 11.61 | 7.64 | — |
| Age | ≤50 years | 8.75 | 7.98 | 0.0003 | >50 years | 14.98 | 8.71 |
| Menopause | Yes | 13.01 | 8.86 | 0.03 | No | 8.78 | 8.23 |
| Lymph nodes involvement | Yes | 15.70 | 8.96 | <0.0001 | No | 8.40 | 7.37 |
| ER status | Positive | 14.05 | 7.83 | 0.03 | Negative | 10.52 | 9.11 |
| PR status | Positive | 15.29 | 7.43 | 0.005 | Negative | 10.18 | 8.98 |
| HER2 status | Positive | 12.71 | 8.36 | 0.20 | Negative | 10.88 | 9.15 |
| TNM stages | Early stage (I & II) | 3.18 | 1.04 | <0.0001 | Advanced stage (III & IV) | 16.78 | 7.41 |
| Distant metastases | Yes | 18.72 | 8.28 | <0.0001 | No | 9.37 | 7.81 |
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