Ginsenoside Rh2 Inhibits Glycolysis through the STAT3/c-MYC Axis in Non-Small-Cell Lung Cancer

Figure 1

Rh2 inhibited NSCLC cells proliferation. (a) Cell viability of A549 and H460 cell lines was detected using CCK-8 assay. (b) The IC50 values of Rh2 for 48 h in A549 and H460 cell lines. (c, d) The NSCLC cells were treated with 40 μg/ml Rh2 for different time intervals (24, 48, and 72 h). The cell viability was detected by CCK-8 and presented as absorbance value (OD). (e) Colony formation assay of NSCLC cells. Clone numbers were counted using a microscope. (f) The morphology changes of NSCLC cells induced by 40 μg/ml Rh2 were observed using a light microscope (10x). Scale bar = 100 μm. Data are shown as mean ± SD of three independent experiments. , , and vs. control groups.

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