Ginsenoside Rh2 Inhibits Glycolysis through the STAT3/c-MYC Axis in Non-Small-Cell Lung Cancer

Figure 6

The inhibitory effect of Rh2 on glycolysis was dependent on the STAT3/c-Myc axis. (a) A549 and H460 cells were transfected with c-Myc expression plasmid for 48 h. The transfection efficiency was detected by western blot, and (b) the relative gray values were shown in a histogram. (c) The color depth of lactate test solution in each group was evaluated visually. (d) The lactate concentration of each group was calculated. (e) The color depth of glucose test solution in each group was evaluated visually. (f) The glucose consumption of each group was calculated. (g) The expression levels of key metabolic enzymes under different treatments were detected by western blotting. Data are shown as mean ± SD of three independent experiments. , vs. control groups. ^#, ^##. ns, not significant. EV, empty vector.

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