Correlation of Peripheral Blood Parameters and Immune-Related Adverse Events with the Efficacy of Immune Checkpoint Inhibitors

Table 4

The correlation of irAEs with response evaluation.

Population	Variable	Number	Percentage (%)	ORR (%)	DCR (%)	ORR (irAE and non-irAE)	DCR (irAE and non-irAE)
Total patient population (93 patients)	PR	16	17.20	17.2	56.99
	SD	37	39.78
	PD	40	43.01
irAE group (33 patients)	PR	10	30.30	30	69.7	= 0.009 (HR = 4.34, 95% CI: 1.43–12.6)	= 0.028 (HR = 2.3, 95% CI: 1.10–4.83)
	SD	13	39.39
	PD	10	30.30
Non-irAE group (60 patients)	PR	6	10.00	10	50
	SD	24	40.00
	PD	30	50.00

^∗Indicators with statistical significance; ORR, objective response rate; DCR, disease control rate.