Construction and Validation of an Autophagy-Related Prognostic Model for Osteosarcoma Patients

Figure 2

Construction of the prognostic risk model based on autophagy-related genes (ARGs) in the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) training cohort using the least absolute shrinkage and selection operator (LASSO) regression analysis. (a) LASSO model with optimal lambda value. (b) LASSO coefficient configuration of the 12 prognostic ARGs. (c) Hazard ratio of the 12 ARGs used for risk model construction. (d), (e) Distribution of risk score and survival status of osteosarcoma patients in the training cohort. (f) Expression of included ARGs in the high- and low-risk groups. (g) Kaplan-Meier analysis of osteosarcoma patients classified by risk score. (h) Receiver operating characteristic (ROC) analysis of risk model in forecasting prognosis.

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