Research Article
Prognostic Value of Albumin to D-Dimer Ratio in Advanced Gastric Cancer
Table 2
Correlations between PFS and patient and tumor characteristics.
| | Univariate analysis | value | Multivariate analysis | value | Hazard ratio | 95% CI | Hazard ratio | 95% CI |
| Age (>59 years) | 0.911 | 0.709–1.171 | 0.467 | | | | Sex (male) | 1.051 | 0.806–1.370 | 0.715 | | | | Body mass index (<18.5 or >25 kg/m2) | 0.971 | 0.731–1.292 | 0.842 | | | | ECOG PS score (>1) | 0.929 | 0.657–1.313 | 0.675 | | | | Pathological differentiation (poorly) | 1.197 | 0.902–1.590 | 0.214 | | | | The number of organs affected by metastasis (>1) | 1.511 | 1.161–1.967 | 0.002 | 1.299 | 0.954–1.768 | 0.096 | Peritoneal metastasis (Yes) | 1.506 | 1.144–1.983 | 0.004 | 1.147 | 0.822–1.602 | 0.419 | TNM staging (IV) | 1.375 | 1.009–1.875 | 0.044 | 1.017 | 0.720–1.436 | 0.924 | CEA (>5 ng/mL) | 1.240 | 0.959–1.604 | 0.101 | 1.134 | 0.857–1.501 | 0.377 | CA19-9 (>37 U/mL) | 0.925 | 0.713–1.200 | 0.558 | | | | CA72-4 (>6 U/mL) | 1.479 | 1.143–1.914 | 0.003 | 1.241 | 0.941–1.636 | 0.126 | Thrombocyte counts (>300 × 109/L) | 1.100 | 0.843–1.435 | 0.483 | | | | ADR (≥41.64) | 0.445 | 0.338–0.585 | <0.001 | 0.509 | 0.380–0.681 | <0.001 |
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ADR, albumin to D-dimer ratio; ECOG PS, eastern cooperative oncology group performance status; CEA, carcinoembryonic antigen; CA72-4, carbohydrate antigen 72-4; CA19-9, carbohydrate antigen 19-9; CI, confidence interval; PFS, progressive-free survival.
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