Research on Effectiveness of Prior Cancer on Survival Outcomes for Patients with Nonmetastatic Triple-Negative Breast Cancer: A Competing Risk Analysis and Propensity Score Matching Analysis of the SEER Database
Table 3
Cumulative incidence function analysis of death causes in woman patients with P-TNBC.
Characteristics
BCSD
OCSD
Event
1 year (%)
3 years (%)
5 years (%)
value
Event
1 year (%)
3 years (%)
5 years (%)
value
Total
n = 682(59.3)
21.7
80.4
96.8
<0.001
n = 469(40.7)
22.6
66.5
93.6
<0.001
Age
<0.001
<0.001
20–39
32 (4.7)
4.0
17.2
22.6
4 (0.9)
0.6
2.1
3.1
40–49
82 (12.0)
2.9
12.2
16.9
26 (5.5)
0.7
3.0
5.8
50–59
140 (20.5)
1.7
11.3
14.8
57 (12.2)
1.2
3.6
6.1
60–69
159 (23.3)
1.9
9.9
13.0
92 (19.6)
1.8
5.1
8.2
70–79
155 (22.7)
3.1
12.1
17.1
138 (29.4)
2.1
9.1
16.0
80+
114 (16.7)
5.8
15.7
20.9
152 (32.4)
5.2
17.1
30.4
Race
0.023
0.113
Black
149 (21.8)
3.2
15.4
18.1
95 (20.3)
2.5
7.6
13.8
White
497 (72.9)
2.8
11.1
15.6
354 (75.5)
1.9
6.7
11.5
Other
36 (5.3)
0.9
10.6
14.8
20 (4.3)
0.9
6.5
8.7
Marital
0.001
<0.001
Married
321 (47.1)
2.0
10.4
14.5
186 (39.7)
1.5
5.4
8.6
Single
361 (52.9)
3.6
13.6
17.8
283 (60.3)
2.5
8.4
15.3
Laterality
0.629
0.430
Left
350 (51.3)
2.0
11.9
15.6
254 (54.2)
1.8
6.6
12.0
Right
332 (48.7)
2.9
11.9
16.6
215 (45.8)
2.2
7.0
11.5
Grade
<0.001
0.127
I
7 (1.0)
0.6
4.2
4.2
12 (2.6)
1.2
5.1
9.3
II
111 (16.3)
1.9
8.1
12.3
87 (18.6)
1.8
5.6
10.3
III
557 (81.7)
3.1
13.2
17.6
364 (77.6)
2.1
7.2
12.2
IV
7 (1.0)
3.0
19.4
23.3
6 (1.3)
3.0
13.1
23.0
T status
<0.001
0.002
T1
211 (30.9)
1.2
6.0
8.4
241 (51.4)
1.5
5.7
10.5
T2
300 (44.0)
3.3
15.8
21.6
174 (37.1)
2.3
7.8
13.3
T3
94 (13.8)
12.3
33.1
43.2
33 (7.0)
3.3
9.7
14.7
T4
77 (11.3)
11.8
46.1
55.2
21 (4.5)
5.3
12.4
13.4
N status
<0.001
0.716
N0
341 (50.0)
1.6
7.9
10.5
352 (75.1)
2.0
6.9
11.5
N1
167 (24.5)
4.1
17.3
25.1
73 (15.6)
1.2
5.9
12.7
N2
79 (11.6)
10.6
33.8
41.9
25 (5.3)
3.5
8.3
13.2
N3
95 (13.9)
13.6
46.9
59.4
19 (4.1)
3.8
8.5
10.5
Surgery
<0.001
0.003
BCS
179 (26.2)
1.6
8.1
11.8
201 (42.9)
2.2
8.2
13.5
Mastectomy
503 (73.8)
3.5
14.1
18.5
268 (57.1)
1.9
6.0
10.8
Radiotherapy
0.991
0.005
No
456 (66.9)
3.3
12.0
16.1
341 (72.7)
2.4
7.6
12.8
Yes
226 (33.1)
1.7
11.8
16.0
128 (27.3)
1.2
5.2
9.6
Chemotherapy
0.287
<0.001
No
263 (38.6)
3.7
11.4
15.0
315 (67.2)
3.6
11.6
19.0
Yes
419 (61.4)
2.2
12.3
16.8
154 (32.8)
0.9
3.6
6.7
Note. P-TNBC: triple-negative breast cancer with prior cancer; BCS: breast-conserving therapy; BCSD: breast cancer-specific death; OCSD: other cause-specific death. value <0.05 was considered statistically significant.
