Research on Effectiveness of Prior Cancer on Survival Outcomes for Patients with Nonmetastatic Triple-Negative Breast Cancer: A Competing Risk Analysis and Propensity Score Matching Analysis of the SEER Database
Table 4
The Fine and Gray proportional subdistribution hazard model for BCSD and OCSD in woman patients with P-TNBC.
Characteristics
BCSD
OCSD
SHR
95% CI
value
SHR
95% CI
value
Age
20–39
1
1
40–49
0.73
0.49–1.11
0.140
1.76
0.61–1.76
0.290
50–59
0.67
0.46–0.98
0.041
1.89
0.68–1.89
0.220
60–69
0.65
0.44–0.95
0.028
2.38
0.87–2.38
0.092
70–79
0.84
0.57–1.23
0.360
3.84
1.41–3.84
0.008
80+
0.91
0.60–1.37
0.630
5.79
2.13–5.79
0.001
Race
Black
1
—
White
0.87
0.72–1.05
0.140
—
—
—
Other
0.75
0.53–1.07
0.120
—
—
—
Marital
Married
1
1
Single
0.92
0.79–1.08
0.330
0.79
0.65–0.79
0.014
Grade
I
1
—
II
2.06
0.90–4.21
0.089
—
—
—
III
3.58
1.04–4.70
0.040
—
—
—
IV
4.42
1.22–10.56
0.020
—
—
—
T status
T1
1
1
T2
2.13
1.71–2.48
<0.001
1.46
1.19–1.46
<0.001
T3
3.80
2.70–4.76
<0.001
1.95
1.33–1.95
0.001
T4
4.67
3.21–6.10
<0.001
2.12
1.31–2.12
0.002
N status
N0
1
—
N1
1.84
1.51–2.24
<0.001
—
—
—
N2
2.75
2.09–3.63
<0.001
—
—
—
N3
4.22
3.24–5.49
<0.001
—
—
—
Surgery
BCS
1
1
Mastectomy
1.17
0.98–1.40
0.480
0.63
0.51–0.63
<0.001
Radiotherapy
No
—
1
Yes
—
—
—
1.56
1.22–1.56
<0.001
Chemotherapy
No
—
1
Yes
—
—
—
2.12
1.71–2.12
<0.001
Note. P-TNBC: triple-negative breast cancer with prior cancers; BCS: breast-conserving therapy; BCSD: breast cancer-specific death; OCSD: other cause-specific death; SHR: subdistribution hazard ratio; 95%CI: 95% confidence interval. value <0.05 was considered statistically significant.
