Research Article

High Expression of COL10A1 Is an Independent Predictive Poor Prognostic Biomarker and Associated with Immune Infiltration in Advanced Gastric Cancer Microenvironment

Table 1

Association between COL10A1 expression and different clinicopathological features of human GC.

CharacteristicLow expression of COL10A1High expression of COL10A1

187188
T stage, (%)<0.001
 T118 (4.9%)1 (0.3%)
 T244 (12%)36 (9.8%)
 T378 (21.3%)90 (24.5%)
 T445 (12.3%)55 (15%)
N stage, (%)0.901
 N053 (14.8%)58 (16.2%)
 N151 (14.3%)46 (12.9%)
 N239 (10.9%)36 (10.1%)
 N337 (10.4%)37 (10.4%)
M stage, (%)1.000
 M0166 (46.8%)164 (46.2%)
 M113 (3.7%)12 (3.4%)
Pathologic stage, (%)0.012
 Stage I36 (10.2%)17 (4.8%)
 Stage II45 (12.8%)66 (18.8%)
 Stage III77 (21.9%)73 (20.7%)
 Stage IV19 (5.4%)19 (5.4%)
Gender, (%)0.884
 Female68 (18.1%)66 (17.6%)
 Male119 (31.7%)122 (32.5%)
Age, (%)0.899
 ≤6582 (22.1%)82 (22.1%)
 >65101 (27.2%)106 (28.6%)
Histologic grade, (%)0.095
 G15 (1.4%)5 (1.4%)
 G277 (21%)60 (16.4%)
 G398 (26.8%)121 (33.1%)
H pylori infection, (%)1.000
 No96 (58.9%)49 (30.1%)
 Yes12 (7.4%)6 (3.7%)
Barrett’s esophagus, (%)0.612
 No122 (58.7%)71 (34.1%)
 Yes11 (5.3%)4 (1.9%)
Age, 0.580