GEMIN6 Overexpression Correlates with the Low Immune Cell Infiltration and Poor Prognosis in Lung Adenocarcinoma

Table 2

The univariate and multivariate analyses of overall survival according to GEMIN6 expression and other prognostic factors.

Characteristics	Total ()	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
T stage (T3-4 vs. T1-2)	523	2.317 (1.591-3.375)	<0.001	1.697 (1.029-2.799)	0.038
N stage (N1-3 vs. N0)	510	2.601 (1.944-3.480)	<0.001	1.966 (1.332-2.901)	<0.001
Pathologic stage (stage III-IV vs. stage I-II)	518	2.664 (1.960-3.621)	<0.001	1.312 (0.828-2.080)	0.247
Primary therapy outcome (PR & SD & PD vs. CR)	439	2.690 (1.918-3.771)	<0.001	2.308 (1.620-3.286)	<0.001
Gender (male vs. female)	526	1.070 (0.803-1.426)	0.642
Race (White vs. Asian & Black or African American)	468	1.475 (0.902-2.411)	0.121
Age (>65 vs. ≤65)	516	1.223 (0.916-1.635)	0.172
Smoker (yes vs. no)	512	0.894 (0.592-1.348)	0.591
Number pack years smoked (≥40 vs. <40)	363	1.073 (0.753-1.528)	0.697
GEMIN6 (high vs. low)	526	1.529 (1.136-2.058)	0.005	1.491 (1.063-2.092)	0.021