Long Noncoding RNA LINC02249 Is a Prognostic Biomarker and Correlates with Immunosuppressive Microenvironment in Skin Cutaneous Melanoma

Table 2

Univariate and multivariate analyses for overall survival in SKCM patients.

Characteristics	Total (N)	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Pathologic stage	410
Stage I and Stage II	217	Reference
Stage III and Stage IV	193	1.617 (1.207–2.165)	0.001	1.723 (1.283–2.314)	<0.001
Gender	456
Female	172	Reference
Male	284	1.172 (0.879–1.563)	0.281
Age	456
≤60	246	Reference
>60	210	1.656 (1.251–2.192)	<0.001	1.461 (1.089–1.962)	0.012
LINC02249	456
Low	226	Reference
High	230	1.724 (1.315–2.260)	<0.001	1.693 (1.267–2.263)	<0.001