Long Noncoding RNA LINC02249 Is a Prognostic Biomarker and Correlates with Immunosuppressive Microenvironment in Skin Cutaneous Melanoma

Table 3

Univariate and multivariate analyses for disease-specific survival in SKCM patients.

Characteristics	Total (N)	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Pathologic stage	405
Stage I and Stage II	215	Reference
Stage III and Stage IV	190	1.536 (1.125–2.096)	0.007	1.632 (1.192–2.233)	0.002
Gender	450
Female	172	Reference
Male	278	1.161 (0.855–1.575)	0.340
Age	450
≤60	244	Reference
>60	206	1.699 (1.258–2.294)	<0.001	1.484 (1.085–2.031)	0.014
LINC02249	450
Low	224	Reference
High	226	1.690 (1.266–2.255)	<0.001	1.627 (1.196–2.213)	0.002