Research Article

CircNRIP1 Exerts Oncogenic Functions in Papillary Thyroid Carcinoma by Sponging miR-653-5p and Regulating PBX3 Expression

Figure 4

Overexpression of PBX3 eliminates the tumor suppressive effect of circNRIP1 knockdown. (a) The efficiency of pcDNA3.1/PBX3 was confirmed by qRT-PCR assay. (b) The PBX3 mRNA expression was evaluated by qRT-PCR assay. (c–e) CCK-8 and EdU incorporation assay were used to detect the cell proliferation. (f) Tunel staining was used to evaluate the apoptosis of tumor cells. (g, h) The cell migration and invasion abilities were detected with transwell assay. .
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