GTPBP4: A New Therapeutic Target Gene Promotes Tumor Progression in Non-Small Cell Lung Cancer via EMT

Figure 5

Knockout of GTPBP4 inhibited NSCLC proliferation in mice. (a) A mouse lung cancer model established by tail vein injection. At 21 days, the complete morphology of the lung tissue removed after the mice were sacrificed. (b) The lung weight of LLC-GTPBP4 KO mice was significantly reduced (n = 10 per group, ). (c) The number of lung tumor nodules in the LLC-GTPBP4 KO group was significantly less than that in the LLC-WT group (n = 10 per group, ). (d) The volume of lung tumor nodules in the LLC-GTPBP4 KO group was significantly smaller than that in the LLC-WT group (n = 10 per group, ).

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