Research Article
GPR30 Activation Promotes the Progression of Gastric Cancer and Plays a Significant Role in the Anti-GC Effect of Huaier
Table 2
The correlations between the GPR30 expression levels and the clinicopathological features of GC patients.
| | GPR30 expression | Total | χ2 | value | High | Low |
| Age (year) | | | | | | <66 | 22 | 21 | 43 | 0.788 | 0.375 | ≥66 | 29 | 19 | 48 | Sex | | | | | | Female | 14 | 5 | 19 | 3.033 | 0.082 | Male | 37 | 35 | 72 | Tumor size (cm) | | | | | | <5 cm | 23 | 29 | 52 | 6.873 | 0.009 | ≥5 cm | 28 | 11 | 39 | Grade of differentiation | | | | | | Well/moderate | 22 | 13 | 35 | 1.072 | 0.301 | Poor/not | 29 | 27 | 56 | T Stage | | | | | | T1/T2 | 4 | 7 | 11 | 1.163 | 0.281 | T3/T4 | 47 | 33 | 80 | N stage | | | | | | N0/N1 | 18 | 17 | 35 | 0.492 | 0.483 | N2/N3 | 33 | 23 | 56 | M Stage | | | | | | M0 | 48 | 40 | 88 | 2.433 | 0.119 | M1 | 3 | 0 | 3 | TNM stage | | | | | | Ι/II | 15 | 11 | 26 | 0.040 | 0.841 | III/IV | 36 | 29 | 65 | CEA (ng/ml) | | | | | | <5 | 41 | 32 | 73 | 0.002 | 0.963 | ≥5 | 10 | 8 | 18 | HER2 | | | | | | Positive | 7 | 2 | 9 | 1.061 | 0.303 | Negative | 44 | 38 | 82 | PD-1 | | | | | | Positive | 13 | 3 | 16 | 2.859 | 0.091 | Negative | 38 | 37 | 75 |
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