Research Article

Transarterial Infusion Chemotherapy with FOLFOX Could be an Effective and Safe Treatment for Unresectable Intrahepatic Cholangiocarcinoma

Table 1

Clinical characteristics of patients.

n = 29

Age (year)51.4 (28.0 – 67.0)
Sex
 Male21 (72.4%)
 Female8 (27.6%)
WBC count (×109/L)7.8 ± 0.5
NE count (×109/L)5.4 ± 0.5
Hgb (g/L)133.6 ± 4.0
PLT count (×109/L)258.6 ± 21.1
ALT (U/L)25.15 (7.2 – 64.2)
ALB (g/L)42.3 ± 0.8
TBil (umol/L)13.0 ± 1.0
PT (s)12.1 ± 0.1
CRE (umol/L)68.7 ± 3.1
AFP (ng/ml)4.5 (1.14 – 18,596.0)
CA19-9 (U/ml)58.9 (0.6 – 20,000.0)
CEA (ng/ml)3.9 (1.02 – 169.8)
HBsAg
 Negative10 (34.5%)
 Positive19 (65.5%)
Anti-HCV
 Negative29 (100.0%)
 Positive0 (0.0%)
HBV-DNA
 ≤1 × 103 copies15 (51.7%)
 >1 × 103 copies14 (48.3%)
Child–Pugh score
 528 (96.6%)
 61 (3.4%)
Maximum diameter of tumor (cm)8.4 ± 0.6
Tumor numbers
 Single12 (41.4%)
 Multiple17 (58.6%)
Tumor distribution
 Unilobe18 (62.1%)
 Bilobe11 (37.9%)
Macrovascular invasion
 Absent20 (69.0%)
 Present9 (31.0%)
Distant metastasis
 Absent18 (62.1%)
 Present11 (37.9%)