Research Article
Low Expression of CD5 and CD6 Is Associated with Poor Overall Survival for Patients with T-Cell Malignancies
Table 1
Univariate and multivariate cox regression analysis in TCM patients.
| Variables | Univariate cox regression | Multivariate cox regression | Training cohort | Validation cohort | Training cohort | Validation cohort | HR (95% CI) | value | HR (95% CI) | value | HR (95% CI) | value | HR (95% CI) | value |
| Sex (ref: female) | | | | | | | | | Male | 0.68 (0.27, 1.71) | 0.412 | 1.60 (0.99, 2.61) | 0.057 | 0.96 (0.36, 2.56) | 0.934 | 1.62 (0.98, 2.68) | 0.060 | Age, years | | | | | | | | | | 0.99 (0.96, 1.02) | 0.564 | 1.02 (1.01, 1.04) | 0.001 | 0.98 (0.95, 1.02) | 0.395 | 1.03 (1.01, 1.04) | 0.001 | CD5/CD6 (ref: CD5lo/CD6 lo) | | | | | | | | | CD5hi or CD6 hi | 0.86 (0.32, 2.32) | 0.765 | 0.44 (0.24, 0.83) | 0.011 | 0.95 (0.34, 2.68) | 0.922 | 0.41 (0.21, 0.80) | 0.010 | CD5hi/CD6 hi | 0.19 (0.04, 0.86) | 0.031 | 0.39 (0.23, 0.65) | < 0.001 | 0.18 (0.04, 0.88) | 0.034 | 0.35 (0.19, 0.62) | < 0.001 |
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Cox regression analysis of data with complete age and gender information. CI: confidence interval; HR: hazard ratio. |