Low Expression of CD5 and CD6 Is Associated with Poor Overall Survival for Patients with T-Cell Malignancies

Table 1

Univariate and multivariate cox regression analysis in TCM patients.

Variables	Univariate cox regression				Multivariate cox regression
	Training cohort		Validation cohort		Training cohort		Validation cohort
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
Sex (ref: female)
Male	0.68 (0.27, 1.71)	0.412	1.60 (0.99, 2.61)	0.057	0.96 (0.36, 2.56)	0.934	1.62 (0.98, 2.68)	0.060
Age, years
	0.99 (0.96, 1.02)	0.564	1.02 (1.01, 1.04)	0.001	0.98 (0.95, 1.02)	0.395	1.03 (1.01, 1.04)	0.001
CD5/CD6 (ref: CD5lo/CD6 lo)
CD5hi or CD6 hi	0.86 (0.32, 2.32)	0.765	0.44 (0.24, 0.83)	0.011	0.95 (0.34, 2.68)	0.922	0.41 (0.21, 0.80)	0.010
CD5hi/CD6 hi	0.19 (0.04, 0.86)	0.031	0.39 (0.23, 0.65)	< 0.001	0.18 (0.04, 0.88)	0.034	0.35 (0.19, 0.62)	< 0.001

Cox regression analysis of data with complete age and gender information. CI: confidence interval; HR: hazard ratio.