Transmembrane Transporter Sema3D Serves as a Tumor Suppressor in Localized Clear Cell Renal Cell Carcinoma

Figure 5

Differential expression and function enrichment analysis based on the RNAseq data of ccRCC from TCGA. (a) PPI network of proteins interacting with Sema3D. (b) Volcano plot showing differentially expressed genes (DEGs) based on Sema3D mRNA expression. The blue dots represent downregulated genes, and the red dots represent upregulated genes. (c) GO and KEGG function analysis of DEGs. The first group represents biological process (BP) group, the second group represents cellular component (CC) group, the third group represents molecular function (MF) group, and the last group represents KEGG group. (d) Pathway enrichment analysis of DEGs based on the hallmark gene sets.

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