Research Article

Transmembrane Transporter Sema3D Serves as a Tumor Suppressor in Localized Clear Cell Renal Cell Carcinoma

Table 1

Demographics and clinical characteristics of ccRCC patients according to the Sema3D expression.

ParametersAll patients (n = 86)Low expression (n = 67)Expression (n = 19) value

Age
 <60 years44 (51.2)35 (52.2)9 (47.4)0.842
 ≥60 years42 (48.8)32 (47.8)10 (52.6)
Gender
 Male46 (53.5)37 (55.2)9 (47.4)0.608
 Female40 (46.5)30 (44.8)10 (52.6)
T stage
 T164 (74.4)48 (71.6)16 (84.2)0.292
 T218 (20.9)15 (22.4)3 (15.8)
 T34 (4.7)4 (6.0)0 (0)
N stage
 N085 (98.8)66 (98.5)19 (100.0)>0.99
 N11 (1.2)1 (1.5)0 (0)
M stage
 M084 (97.7)65 (97.0)19 (100.0)>0.99
 M12 (2.3)2 (3.0)0 (0)
AJCC stage
 I/II81 (94.2)62 (92.5)19 (100.0)0.462
 III/IV5 (5.8)5 (7.5)0 (0)
Fuhrman grade
 I/II72 (83.7)55 (82.1)17 (89.5)0.514
 III/IV14 (16.3)12 (17.9)2 (10.5)
Median tumor maximal diameter (cm)5.05.05.50.965